胚胎发育相关蛋白Nodal抗体费用 英文名称  Anti-Nodal

中文名称  胚胎发育相关蛋白Nodal抗体费用 

别    名 MGC138230; Nodal; nodal homolog (mouse); Nodal homolog; NODAL_HUMAN.

产品属性：

浓    度  1mg/1ml

规 格  0.2ml/200μg

抗体来源  Rabbit

克隆类型   polyclonal

交叉反应   Human, Mouse, Rat, Dog, Cow, Horse, Rabbit, Sheep

产品类型   一抗  

研究领域    发育生物学 神经生物学 干细胞 转录调节因子

蛋白分子量  predicted molecular weight: 13kDa 

性    状   Lyophilized or Liquid

免 疫 原  KLH conjugated synthetic peptide derived from Human Nodal

亚    型  IgG

纯化方法   affinity purified by Protein A

储 存 液   Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4

胚胎发育相关蛋白Nodal抗体费用 产品应用   WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500

（石蜡切片需做抗原修复） 

 not yet tested in other applications.

 optimal dilutions/concentrations should be determined by the end user.  

保存条件  Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. 

Important Note  This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. 

产品介绍 The transforming growth factor Beta (TGF Beta) superfamily is composed of numerous growth and differentiation factors, including TGF Beta 1-3, Mullerian inhibiting substance (MIS), growth/differentiation factor (GDF) 1-9, bone morphogenic protein (BMP) 2-8, glial cell line-derived neurotrophic factor (GDNF), Inhibin Alpha, Beta-A, Beta-B and Beta-C, Lefty and Nodal. Members of the TGF Beta superfamily are involved in embryonic development and adult tissue homeostasis. Ectodermal cells through the primitive streak delaminate and differentiate into mesoderm during gastrulation. Nodal expression is detectable in the primitive streak at the time of mesoderm formation, indicating a potential role for Nodal in mesoderm formation. Nodal has also been shown to be involved in the direction of heart looping and embryonic turning.

Function : Essential for mesoderm formation and axial patterning during embryonic development.Subunit : Homodimer; disulfide-linked (By similarity).Subcellular Location : Secreted.DISEASE : Defects in NODAL are the cause of visceral heterotaxy autosomal type 5 (HTX5) [MIM:270100]. A form of visceral heterotaxy, a complex disorder due to disruption of the normal left-right asymmetry of the thoracoabdominal organs. It results in an abnormal arrangement of visceral organs, and a wide variety of congenital defects. Clinical features of visceral heterotaxy autosomal type 5 include situs inversus viscerum or situs ambiguus, congenital heart defect, transposition of the great vessels ventricular septal defect, atrial septal defect, truncuscommunis, and dextrocardia.Similarity : Belongs to the TGF-beta family.Database links : UniProtKB/Swiss-Prot: Q96S42.2

实验流程：

全、新、优、品、好四大特点：

胚胎发育相关蛋白Nodal抗体费用 全：公司提供上万种产品，涵盖了生物试剂，elisa试剂盒，标准品，培养基，原装耗材，抗体、培养基、ATCC细胞等，基本上各种科研所需产品在我司都能找到。

新：产品更新速度较快，基本上每周都有新产品出现。

优：产品质量好，投诉比较少。

好：我公司具有优质的技术团队，产品一旦售出，实验过程中遇到困难可提供在线技术咨询。使您使用产品时没有任何的后顾之忧。

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