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脑特异性跨膜蛋白抗体说明书
  • 品牌:上海莼试
  • 产地:进口、国产
  • 货号:CS9756
  • 发布日期: 2018-12-25
  • 更新日期: 2025-11-12
产品详请
产地 进口、国产
品牌 上海莼试
保存条件 Store at -20 °C
货号 CS9756
应用范围 WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 Flow-Cyt=1:100-500 ICC=1:100-500 IF=1:100-500
CAS编号
抗体名 Anti-NETO2
克隆性
靶点 详见说明书
适应物种 详见说明书
形态 详见说明书
宿主 详见说明书
亚型 IgG
标识物 详见说明书
浓度 1mg/1ml%
免疫原 KLH conjugated synthetic peptide derived from human NETO2

全、新、优、品、好四大特点:

脑特异性跨膜蛋白抗体说明书 全:公司提供上万种产品,涵盖了生物试剂,elisa试剂盒,标准品,培养基,原装耗材,抗体、培养基、ATCC细胞等,基本上各种科研所需产品在我司都能找到。

新:产品更新速度较快,基本上每周都有新产品出现。

优:产品质量好,投诉比较少。

好:我公司具有优质的技术团队,产品一旦售出,实验过程中遇到困难可提供在线技术咨询。使您使用产品时没有任何的后顾之忧。

脑特异性跨膜蛋白抗体说明书 英文名称  Anti-NETO2

中文名称  脑特异性跨膜蛋白抗体说明书 

     Brain specific transmembrane protein; Brain specific transmembrane protein containing 2 CUB and 1 LDL receptor class A domains protein 2; Brain-specific transmembrane protein containing 2 CUB and 1 LDL-receptor class A domains protein 2; BTCL2; FLJ10430; FLJ14724; FLJ90456; NEOT2; NETO 2; Neto2; NETO2_HUMAN; Neuropilin (NRP) and tolloid (TLL) like 2; Neuropilin and tolloid like protein 2; Neuropilin and tolloid-like protein 2.

产品属性:

      1mg/1ml

  0.2ml/200μg

抗体来源  Rabbit

克隆类型   polyclonal

交叉反应   Human, Mouse, Rat, Dog, Pig, Cow, Sheep

产品类型   一抗  

研究领域    神经生物学 通道蛋白 细胞膜蛋白

蛋白分子量  predicted molecular weight: 57kDa 

       Lyophilized or Liquid

  KLH conjugated synthetic peptide derived from human NETO2

      IgG

纯化方法   affinity purified by Protein A

   Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4

脑特异性跨膜蛋白抗体说明书 产品应用   WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 Flow-Cyt=1:100-500 ICC=1:100-500 IF=1:100-500

(石蜡切片需做抗原修复) 

 not yet tested in other applications.

 optimal dilutions/concentrations should be determined by the end user.  

保存条件  Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. 

Important Note  This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. 

产品介绍 NETO2 is a 525 amino acid single-pass type I membrane protein that contains two CUB domains and one LDL-receptor class A domain. Expressed as multiple alternatively spliced isoforms, NETO2 is thought to play a role in the development and maintenance of neuronal circuitry, possibly playing a role in proper brain function. The gene encoding NETO2 maps to human chromosome 16, which is associated with a variety of genetic disorders, encodes over 900 genes and comprises nearly 3% of the human genome. The GAN gene is located on chromosome 16 and, with mutation, may lead to giant axonal neuropathy, a nervous system disorder characterized by increasing malfunction with growth. The rare disorder Rubinstein-Taybi syndrome is associated with chromosome 16, as is Crohn's disease, which is a gastrointestinal inflammatory condition。

Function : Accessory subunit of neuronal kainate-sensitive glutamate receptors, GRIK2 and GRIK3. Increases kainate-receptor channel activity, slowing the decay kinetics of the receptors, without affecting their expression at the cell surface, and increasing the open probability of the receptor channels. Modulates the agonist sensitivity of kainate receptors. Slows the decay of kainate receptor-mediated excitatory postsynaptic currents (EPSCs), thus directly influencing synaptic transmission.Subunit : Interacts with GRIK2 and GRIK3, but neither with AMPA-nor with NMDA-sensitive glutamate receptorsSubcellular Location : Membrane.Post-translational modifications : N-glycosylated.Similarity : Contains 2 CUB domains.Contains 1 LDL-receptor class A domain.Database links : UniProtKB/Swiss-Prot: Q8NC67.1

实验流程:

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