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| 产地 | 进口、国产 |
| 品牌 | 上海莼试 |
| 保存条件 | Store at -20 °C |
| 货号 | CS9773 |
| 应用范围 | WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 Flow-Cyt=1:100-500 ICC=1:100-500 IF=1:100-500 |
| CAS编号 | |
| 抗体名 | Anti-NTR1/Neurotensin Receptor 1 |
| 克隆性 | |
| 靶点 | 详见说明书 |
| 适应物种 | 详见说明书 |
| 形态 | 详见说明书 |
| 宿主 | 详见说明书 |
| 亚型 | IgG |
| 标识物 | 详见说明书 |
| 浓度 | 1mg/1ml% |
| 免疫原 | KLH conjugated synthetic peptide derived from human NTR1/Neurotensin Receptor 1 |
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神经降压素受体1抗体费用 英文名称 Anti-NTR1/Neurotensin Receptor 1
中文名称 神经降压素受体1抗体费用
别 名 High affinity levocabastine insensitive neurotensin receptor; Neurotensin receptor type 1; NT R 1; NTR; NTR1; NTRH; NTRR; NTR-1; NTSR 1; NTR1_HUMAN.
产品属性:
浓 度 1mg/1ml
规 格 0.2ml/200μg
抗体来源 Rabbit
克隆类型 polyclonal
交叉反应 Human
产品类型 一抗
研究领域 细胞生物 神经生物学 信号转导 细胞膜受体 G蛋白偶联受体 G蛋白信号
蛋白分子量 predicted molecular weight: 46kDa
性 状 Lyophilized or Liquid
免 疫 原 KLH conjugated synthetic peptide derived from human NTR1/Neurotensin Receptor 1
亚 型 IgG
纯化方法 affinity purified by Protein A
储 存 液 Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4
神经降压素受体1抗体费用 产品应用 WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 Flow-Cyt=1:100-500 ICC=1:100-500 IF=1:100-500
(石蜡切片需做抗原修复)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
Important Note This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
产品介绍 Neurotensin (NT) initiates an intracellular response by interacting with the G protein-coupled receptors NTR1 (NTS1 receptor, high affinity NTR) and NTR2 (NTS2 receptor, levocabastine-sensitive Neurotensin receptor), and the type I receptor NTR3 (NTS3 receptor, sortilin-1, Gp95). Neurotensin has a wide distribution in regions of the brain and in peripheral tissues where Neuro-tensin receptors can contribute to hypotension, hyperglycemia, hypothermia, antinociception and regulation of intestinal motility and secretion. HL-60 cells express NTR1, which can couple to Gq, Gi/o, or Gs. Alternative splicing of rat NTR2 can generate a five-transmembrane domain variant isoform that is co-expressed with the full-length NTR2 throughout the brain and spinal cord. NTR3 activation in the murine microglial cell line N11 induces MIP-2, MCP-1, IL-1b and TNFa in an ERK1/2- and Akt kinase-dependent manner.
Function : Neurotensin receptor 1 belongs to the large superfamily of G-protein coupled receptors. NTSR1 mediates the multiple functions of neurotensin, such as hypotension, hyperglycemia, hypothermia, antinociception, and regulation of intestinal motility and secretion. NTR1 has been reported in brain, pancreas, and small intestine. ESTs have been isolated from brain and colon libraries.Subcellular Location : ell membrane; Multi-pass membrane protein.Similarity : Belongs to the G-protein coupled receptor 1 family. Neurotensin receptor subfamily. NTSR1 sub-subfamily.Database links : UniProtKB/Swiss-Prot: P30989.2
实验流程:

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