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| 产地 | 进口、国产 |
| 品牌 | 上海莼试 |
| 保存条件 | Store at -20 °C |
| 货号 | CS9876 |
| 应用范围 | WB=1:100-500 ELISA=1:500-1000 IP=1:20-100 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 |
| CAS编号 | |
| 抗体名 | Anti-NGF-β |
| 克隆性 | |
| 靶点 | 详见说明书 |
| 适应物种 | 详见说明书 |
| 形态 | 详见说明书 |
| 宿主 | 详见说明书 |
| 亚型 | IgG |
| 标识物 | 详见说明书 |
| 浓度 | 1mg/1ml% |
| 免疫原 | KLH conjugated synthetic peptide derived from human NGF beta C-terminus |
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神经生长因子β抗体说明书 英文名称 Anti-NGF-β
中文名称 神经生长因子β抗体说明书
别 名 Beta nerve growth factor; NGF-beta; NGF β; β NGF; β-NGF; Beta nerve growth factor precursor; Beta NGF; HSAN5; MGC161426; MGC161428; Nerve growth factor beta; Nerve growth factor beta polypeptide; Nerve growth factor beta subunit; NGF B; NGFB; NID67; NGF beta; NGF-B.
产品属性:
浓 度 1mg/1ml
规 格 0.1ml/100μg 0.2ml/200μg
抗体来源 Rabbit
克隆类型 polyclonal
交叉反应 Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Horse, Rabbit
产品类型 一抗
研究领域 发育生物学 神经生物学
蛋白分子量 predicted molecular weight: 13kDa
性 状 Lyophilized or Liquid
免 疫 原 KLH conjugated synthetic peptide derived from human NGF beta C-terminus
亚 型 IgG
纯化方法 affinity purified by Protein A
储 存 液 0.01M PBS, pH 7.4 with 10 mg/ml BSA and 0.1% Sodium azide
神经生长因子β抗体说明书 产品应用 WB=1:100-500 ELISA=1:500-1000 IP=1:20-100 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500
(石蜡切片需做抗原修复)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
Important Note This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
产品介绍 Neurotrophins function to regulate naturally occuring cell death of neurons during development .The prototype neurotrophin is nerve growth factor (NGF),originally discovered in the 1950s as a soluble peptide promoting the survival of and veurite outgrowth from, sympathetic ganglia. More recently,three additional structurally homologous neurotrophic factor have been identified.These include brain-derived neurotrophic factor (BDNF), neurotrophic-3 (NT-3) neurotrophic-4(NT-4), also designated NT-5. These neurous neurotrophic stimulate the in vitro survival of distinct but partilly overlapping populations of neurons. The Trk A receptor is the preferential receptor for NGF, but also binds NT-3and NT-4. The Trk B receptor binds equally well both BDNF and NT-4, and to a lesser extent NT-3, while the Trk C receptor only binds NT-3.
Function : Nerve growth factor is important for the development and maintenance of the sympathetic and sensory nervous systems. Extracellular ligand for the NTRK1 and NGFR receptors, activates cellular signaling cascades through those receptor tyrosine kinase to regulate neuronal proliferation, differentiation and survival.Subunit : Homodimer.Subcellular Location : Secreted.DISEASE : Defects in NGF are the cause of hereditary sensory and autonomic neuropathy type 5 (HSAN5) [MIM:608654]. The hereditary sensory and autonomic neuropathies are a genetically and clinically heterogeneous group of disorders characterized by degeneration of dorsal root and autonomic ganglion cells, and by sensory and/or autonomic abnormalities. HSAN5 patients manifest loss of pain perception and impaired temperature sensitivity, ulcers, and in some cases self-mutilation. The autonomic involvement is variable.Similarity : Belongs to the NGF-beta family.Database links : UniProtKB/Swiss-Prot: P01138.3神经生长因子-β(NGF-β)属于一种对神经元的生长、分化、延长存活期有促进作用的神经生长因子家族。此抗体识别分子量为29kDa 的NGF蛋白。神经生长因子(Nerve Growth Factor,NGF)是最早被发现、兼有神经元营养和促突触生长双重生物学功能的一种细胞,可.
实验流程:

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