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| 产地 | 进口、国产 |
| 品牌 | 上海莼试 |
| 保存条件 | Store at -20 °C |
| 货号 | CS9970 |
| 应用范围 | WB=1:100-500 ELISA=1:500-1000 IP=1:20-100 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 |
| CAS编号 | |
| 抗体名 | Anti-Nrn1/Cpg15/Neuritin |
| 克隆性 | |
| 靶点 | 详见说明书 |
| 适应物种 | 详见说明书 |
| 形态 | 详见说明书 |
| 宿主 | 详见说明书 |
| 亚型 | IgG |
| 标识物 | 详见说明书 |
| 浓度 | 1mg/1ml% |
| 免疫原 | KLH conjugated synthetic peptide derived from human Nrn1 C-terminus |
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转化神经突起蛋白抗体规格 英文名称 Anti-Nrn1/Cpg15/Neuritin
中文名称 转化神经突起蛋白抗体规格
别 名 Neuritin; Neuritin 1; NRN; NRN1; OTTHUMP00000015989; RP3 380B8.2 protein.
产品属性:
浓 度 1mg/1ml
规 格 0.2ml/200μg
抗体来源 Rabbit
克隆类型 polyclonal
交叉反应 Human, Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit
产品类型 一抗
研究领域 神经生物学
蛋白分子量 predicted molecular weight: 16kDa
性 状 Lyophilized or Liquid
免 疫 原 KLH conjugated synthetic peptide derived from human Nrn1 C-terminus
亚 型 IgG
纯化方法 affinity purified by Protein A
储 存 液 0.01M PBS, pH 7.4 with 10 mg/ml BSA and 0.1% Sodium azide
转化神经突起蛋白抗体规格 产品应用 WB=1:100-500 ELISA=1:500-1000 IP=1:20-100 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500
(石蜡切片需做抗原修复)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
Important Note This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
产品介绍 function to regulate naturally occurring cell death of neurons during development. The prototype neurotrophin is nerve growth factor (NGF). NGF is a soluble peptide that promotes the survival of, and neurite outgrowth from, sympathetic ganglia. Three additional structurally homologous neurotrophic factors have been identified. These include brain-derived neurotrophic factor (BDNF), neurotrophin-3 (NT-3), and neurotrophin-4 (NT-4, also designated NT-5). Neuritin is a glycosylphosphatidylinositol-anchored protein that is induced by neural activity as well as by BDNF and NT-3. Neuritin modulates neurite growth extracellularly and is present in development and in the adult nervous system, indicating its involvement in neuronal plasticity. In addition to BDNF induction of Neuritin, it has been shown that both Neuritin and BDNF are induced by light stimulation of the visual cortex. Neuritin appears to be located downstream of BDNF and may mediate some of the effects of BDNF
Function : Neuritin is expressed in postmitotic-differentiating neurons of the developmental nervous system and neuronal structures associated with plasticity in the adult. The expression of the Neuritin gene can be induced by neural activity and neurotrophins. The protein contains a consensus cleavage signal found in glycosylphoshatidylinositol (GPI)-anchored proteins. In vitro assays demonstrated that this protein promotes neurite outgrowth and arborization, suggesting its role in promoting neuritogenesis.Subcellular Location : Cell Membrane神经生物学相关蛋白(Neurobiology)
实验流程:

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