技术外包服务:

★视网膜母细胞瘤相关蛋白p130抗体规格 分子生物学：质粒抽提、PCR、Q-PCR、RT-PCR、分子生物学：基因合成、引物合成、基因测序、载体构建等

★蛋白工程：原核、哺乳动物蛋白表达系统等

★病毒包装：腺病毒、慢病毒等

★抗体工程：磁珠分选、病理染色、WB、ELISA、IP、IF、IHC、FACS、Confocal等等

★细胞工程：细胞表型分析(凋亡、增殖、周期、迁移、侵袭、修复、克隆形成)、细胞培养、细胞膜制备、稳定细胞株构建、细胞RNAi技术等等。

实验流程：

视网膜母细胞瘤相关蛋白p130抗体规格 英文名称  Anti-PRB2/p130

中文名称  视网膜母细胞瘤相关蛋白p130抗体规格 

别    名 130 kDa retinoblastoma associated protein; PRB2; Rb2; RBL2; RBR 2; RBR2; RBR-2; Retinoblastoma like 2.

产品属性：

浓    度  1mg/1ml

规 格  0.1ml/100μg 0.2ml/200μg

抗体来源  Rabbit

克隆类型   polyclonal

交叉反应   Human, Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit

产品类型   一抗  

研究领域     细胞生物 免疫学 染色质和核信号 细胞周期蛋白

蛋白分子量  predicted molecular weight: 125kDa 

性    状   Lyophilized or Liquid

免 疫 原  KLH conjugated synthetic peptide derived from human PRB2/p130

亚    型  IgG

纯化方法   affinity purified by Protein A

储 存 液   0.01M PBS, pH 7.4 with 10 mg/ml BSA and 0.1% Sodium azide

视网膜母细胞瘤相关蛋白p130抗体规格 产品应用   WB=1:100-500 ELISA=1:500-1000 IP=1:20-100 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500

（石蜡切片需做抗原修复） 

 not yet tested in other applications.

 optimal dilutions/concentrations should be determined by the end user.  

保存条件  Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. 

Important Note  This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. 

产品介绍 p130 is related both in structure and function to the retinoblastoma tumor suppressor protein and p107 (collectively known as pocket proteins) and is known to regulate the activity of E2F transcription factors. E2F transcription factors regulate the expression of a number of genes important in cell proliferation, particularly those involved in the progression through G1 and into the S phase of the cell cycle. Binding of p130 converts E2F transcription factors from transcriptional activators to transcriptional repressors.

Function : Key regulator of entry into cell division. Directly involved in heterochromatin formation by maintaining overall chromatin structure and, in particular, that of constitutive heterochromatin by stabilizing histone methylation. Recruits and targets histone methyltransferases SUV420H1 and SUV420H2, leading to epigenetic transcriptional repression. Controls histone H4 'Lys-20' trimethylation. Probably acts as a transcription repressor by recruiting chromatin-modifying enzymes to promoters. Potent inhibitor of E2F-mediated trans-activation, associates preferentially with E2F5. Binds to cyclins A and E. Binds to and may be involved in the transforming capacity of the adenovirus E1A protein. May act as a tumor suppressor.

Subunit : Interacts with AATF. Interacts with SUV420H1, SUV420H2 and USP4 (By similarity).

Subcellular Location : Nucleus.

全、新、优、品、好四大特点：

视网膜母细胞瘤相关蛋白p130抗体规格 全：公司提供上万种产品，涵盖了生物试剂，elisa试剂盒，标准品，培养基，原装耗材，抗体、培养基、ATCC细胞等，基本上各种科研所需产品在我司都能找到。

新：产品更新速度较快，基本上每周都有新产品出现。

优：产品质量好，投诉比较少。

好：我公司具有优质的技术团队，产品一旦售出，实验过程中遇到困难可提供在线技术咨询。使您使用产品时没有任何的后顾之忧。

正在热销的相关产品：

TIMP-3(Human tissue inhibitors of metalloproteinase 3) ELISA Kit 人基质金属蛋白酶抑制因子3Multi-class antibodies规格： 48T

Anti-HPL/PL 人胎盘泌乳素抗体Multi-class antibodies规格： 0.2ml

Rhesus antibody Rh MCKD2/UMOD 尿调节蛋白抗体 规格 0.1ml

PRSS(Human serine protease) ELISA Kit 人丝酸蛋白酶 96T

RASSF3 英文名称： Ras相关区域家族1A抗体 0.2ml

C1orf146 英文名称： 1号染色体开放阅读框146抗体 0.2ml

Anti-HPL/PL 人胎盘泌乳素抗体Multi-class antibodies规格： 0.2ml

sICAM-1 human 人可溶性细胞间粘附分子-1Multi-class antibodies规格： 48T

Anti-Collagen IV 抗IV型胶原抗体Multi-class antibodies规格： 0.1ml

Rhesus antibody Rh NOL8 核仁蛋白8抗体 规格 0.2ml

Human rudimental bovine serum albumin check-up ELISA Kit 人的血清白蛋白残留检测 96T

phospho-Tau protein(Ser262) 英文名称： 磷酸化微管相关蛋白抗体 0.1ml

CYP11A1 英文名称： 细胞色素P450 11A1抗体 0.1ml

Anti-Collagen IV 抗IV型胶原抗体Multi-class antibodies规格： 0.1ml

Anti-KLF5/FITC 荧光素标记肠道内富含的Kruppel样因子5抗体IgGMulti-class antibodies规格： 0.2ml

Anti-SLC24A5/FITC 荧光素标记可溶性载质转运蛋白SLC24A5抗体IgGMulti-class antibodies规格： 0.2ml

Rhesus antibody Rh Alpha casein α酪蛋白抗体 规格 0.2ml

Rabbit Anti-human IgM/Cy5.5 Cy5.5标记的兔抗人IgM 0.1ml

GMPPB 英文名称： GDP甘露糖焦磷酸化酶B抗体 0.2ml

Rhesus antibody Rh Rabbit Anti-Guinea pig IgM/Cy3 Cy3标记的兔抗豚鼠IgM 规格 0.1ml

Anti-SLC24A5/FITC 荧光素标记可溶性载质转运蛋白SLC24A5抗体IgGMulti-class antibodies规格： 0.2ml

大鼠卵泡抑素(FS)ELISA 试剂盒 96T/48T 试剂盒 组装/原装

人肾素(Renin)免疫试剂盒 Human renin,REN ELISA Kit

MouseGlycatedhemoglobinA1c,A1cELISAKit小鼠A1c(A1c)ELISA试剂盒规格：96T/48T

swinemajorhistocompatibilitycomplexⅢ,MHCⅢ/SLAⅢELISA试剂盒猪主要组织相容性复合体Ⅲ类(MHCⅢ/SLAⅢ)ELISA试剂盒规格：96T/48T

HumanMaixmetalloproteinase3,MMP-3ELISA试剂盒人基质金属蛋白酶3(MMP-3)ELISA试剂盒规格：96T/48T

HumanPhospholipidaseA2，PL-A2ELISAKit人磷脂酶A2(PL-A2)ELISA试剂盒规格：96T/48T

大鼠补体蛋白4(C4)ELISA试剂盒 ，英文名： C4 ELISA Kit

Mouse alpha 1 acid glycoprotein (1-AGP) ELISA Kit 小鼠α1酸性糖蛋白(α1-AGP)ELISA试剂盒

ELISA 小鼠内皮素-1(mouse Endothelin-1) 48T/96T 进口分装

CLIAKitforKP(Humankaliureticpeptide)ELISAKit人肽规格：48T/96T

通用型半胱氨酸(cysteine)含量比色法定量检测试剂盒20次

ELISAKitt-PA大鼠组织型纤溶酶原激活剂规格：48T/96T

视网膜母细胞瘤相关蛋白p130抗体规格 大鼠蛋白质二硫键异构酶(PDI)ELISA 试剂盒 96T/48T 试剂盒 组装/原装

人内皮素1(ET-1)免疫试剂盒 human Endothelin 1,ET-1 ELISA Kit

MouseterminalcomplemecomplexC5b-9,TCCC5b-9ELISAKit小鼠末端补体复合物C5b-9(TCCC5b-9)ELISA试剂盒规格：96T/48T

冰冻切片组织组蛋白NBT显色光学显微镜检测试剂盒10/20次

HumanPlatelet-DerivedGrowthFactorSolubleReceptorα,PDGFsR-αELISA试剂盒人血血小板衍生生长因子可溶性受体α(PDGFsR-α)ELISA试剂盒规格：96T/48T

HumanSuperOxidaseDimase,SODELISAKit人超氧化物歧化酶(SOD)ELISA试剂盒规格：96T/48T