B淋巴细胞诱导成熟蛋白1抗体说明书 英文名称  Anti-PRDM1/Blimp1

中文名称  B淋巴细胞诱导成熟蛋白1抗体说明书 

别    名 Blimp 1; Blimp-1; B Lymphocyte Induced Maturation Protein 1; Beta interferon gene positive regulatory domain I binding factor; Beta-interferon gene positive regulatory domain I-binding factor; BLIMP-1; BLIMP1; Positive Regulatory Domain I Binding Factor 1; Positive regulatory domain I-binding factor 1; PR Domain Containing 1; PR domain containing 1 with ZNF domain; PR domain containing 1 with ZNF domain isoform 2; PR domain containing protein 1; PR domain zinc finger protein 1; PR domain-containing protein 1; PRDI BF1; PRDI binding factor 1; PRDI-BF1; PRDI-binding factor 1; PRDM 1; Prdm1; PRDM1_HUMAN.

产品属性：

浓    度  1mg/1ml

规 格  0.2ml/200μg

抗体来源  Rabbit

克隆类型   polyclonal

交叉反应   Human, Mouse, Rat, Chicken, Pig, Cow, Horse, Rabbit

产品类型   一抗  

研究领域    细胞生物 免疫学 信号转导 表观遗传学

蛋白分子量  predicted molecular weight: 92kDa 

性    状   Lyophilized or Liquid

免 疫 原  KLH conjugated synthetic peptide derived from human PRDM1/Blimp1

亚    型  IgG

纯化方法   affinity purified by Protein A

储 存 液   Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4

B淋巴细胞诱导成熟蛋白1抗体说明书 产品应用   WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:50-200

（石蜡切片需做抗原修复） 

 not yet tested in other applications.

 optimal dilutions/concentrations should be determined by the end user.  

保存条件  Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. 

Important Note  This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. 

产品介绍 The development and differentiation of plasma cells, which are terminally differentiated B-cells, are induced by Blimp-1 (B lymphocyte-induced maturation protein, also designated PRDI-BF1). Blimp-1 is a transcriptional repressor that localizes to the nucleus and is considered a master regulator of terminal B-cell development. Alone, Blimp-1 is sufficient to trigger terminal B-cell differentiation. Blimp-1 upregulates the expression of syndecan-1 and J chain, represses IFN-b gene transcription and associates with HDAC to recruit it to DNA, thereby repressing c-myc. Blimp-1 is expressed during the late stages of B-cell differentiation in immunoglobulin-secreting plasma cells, as well as in long-lived, bone marrow plasma cells. The expression of Blimp-1 defines a checkpoint beyond which fully activated B cells proceed to the plasma cell stage, whereas immature and partially activated cells are eliminated.

Function : Transcriptional repressor that binds specifically to the PRDI element in the promoter of the beta-interferon gene. Drives the maturation of B-lymphocytes into Ig secreting cells.

Subunit : Interacts with PRMT5.

Subcellular Location : Nucleus. Cytoplasm.

Contains 1 SET domain.

Database links : UniProtKB/Swiss-Prot: O75626.2

实验流程：

全、新、优、品、好四大特点：

B淋巴细胞诱导成熟蛋白1抗体说明书 全：公司提供上万种产品，涵盖了生物试剂，elisa试剂盒，标准品，培养基，原装耗材，抗体、培养基、ATCC细胞等，基本上各种科研所需产品在我司都能找到。

新：产品更新速度较快，基本上每周都有新产品出现。

优：产品质量好，投诉比较少。

好：我公司具有优质的技术团队，产品一旦售出，实验过程中遇到困难可提供在线技术咨询。使您使用产品时没有任何的后顾之忧。

正在热销的相关产品：

Human Cyclin-D1 ELISA Kit 人细胞周期素D1Multi-class antibodies规格： 48T

Anti-HLA G 人类白细胞抗原G抗体Multi-class antibodies规格： 0.2ml

Rhesus antibody Rh MCT1 单羧酸转运蛋白-1抗体 规格 0.2ml

Human Elastase ELISA Kit 人弹性蛋白酶 96T

RASSF5 英文名称： RASSF5抗体 0.2ml

alpha COP I 英文名称： COPA蛋白抗体 0.2ml

Anti-HLA G 人类白细胞抗原G抗体Multi-class antibodies规格： 0.2ml

HGF human 人肝生素Multi-class antibodies规格： 48T

Anti-Collagen III 抗Ⅲ型胶原抗体Multi-class antibodies规格： 0.1ml

Rhesus antibody Rh nonstructural protein 1/NS1 A型病毒-NS1抗体(神经氨酸酶1) 规格 0.2ml

Human myelin basic protein,MBP ELISA Kit 人髓磷脂碱性蛋白 96T

Triosephosphate isomerase 英文名称： 磷酸丙糖异构酶抗体 0.2ml

phospho-CXCR2 (Ser347) 英文名称： 磷酸化细胞表面趋化因子受体2抗体 0.2ml

Anti-Collagen III 抗Ⅲ型胶原抗体Multi-class antibodies规格： 0.1ml

Anti-KLF6/FITC 荧光素标记转染基因KLF6抗体IgGMulti-class antibodies规格： 0.2ml

Anti-SLC33A1/FITC 荧光素标记乙酰辅酶A转运蛋白1抗体IgGMulti-class antibodies规格： 0.2ml

Rhesus antibody Rh Alpha B Crystallin/HSPB5 热休克蛋白β5抗体 规格 0.1ml

Rabbit Anti-human IgM/Cy5 Cy5标记的兔抗人IgM 0.1ml

GMP Synthase 英文名称： 谷酰胺转移酶GMPS抗体 0.2ml

Rhesus antibody Rh Rabbit Anti-Guinea pig IgM/Bio 生物素标记的兔抗豚鼠IgM 规格 0.3ml

Anti-SLC33A1/FITC 荧光素标记乙酰辅酶A转运蛋白1抗体IgGMulti-class antibodies规格： 0.2ml

大鼠标志物CA125ELISA 试剂盒 96T/48T 试剂盒 组装/原装

人肾上腺髓质素前体(Pro-ADM)免疫试剂盒 Human Proadrenomedullin,Pro-ADM ELISA Kit

MouseGlycogenphosphorylaseBB,GP-BBELISAKit小鼠糖原磷酸化酶同工酶BB(GP-BB)ELISA试剂盒规格：96T/48T

tComplemefragme4a,C4aELISA试剂盒大鼠过敏毒素/补体片断4a(C4a)ELISA试剂盒规格：96T/48T

Humanmaixmetalloproteinase4,MMP-4ELISA试剂盒人基质金属蛋白酶4(MMP-4)ELISA试剂盒规格：96T/48T

HumanPhosphorylatedacetylCoA,PaCoAELISAKit人磷酸化乙酰辅酶A(PaCoA)ELISA试剂盒规格：96T/48T

大鼠补体蛋白3(C3)ELISA试剂盒 ，英文名： C3 ELISA Kit

Mouse alpha 1 microglobulin (alpha 1-MG) ELISA Kit 小鼠α1微球蛋白(α1-MG)ELISA试剂盒

ELISA 小鼠噬酸性粒细胞趋化因子(mouse Eotaxin) 48T/96T 进口分装

CLIAKitforKLR(Humankillercelllectin-likereceptor)ELISAKit人杀伤细胞凝集素样受体规格：48T/96T

通用型半胱氨酸(cysteine)含量高效液相色谱法定量检测试剂盒20次

ELISAKitTPA大鼠组织多肽抗原规格：48T/96T

B淋巴细胞诱导成熟蛋白1抗体说明书 大鼠蛋白酶激活受体3(PAR3)ELISA试剂盒 ，英文名： PAR3 ELISA Kit

H-ras ELISA Kit 人H-ras ELISA试剂盒

Ratleukemiainhibitoryfactor,LIFELISAKit 大鼠抑制因子(LIF)ELISA试剂盒 96T/48T 进口分装

CLIAKitforCYP21B(HumanCytochromeP450c21/21-hydroxylase)ELISAKit人细胞色素P450c21B/21-羟化酶规格：48T/96T

细胞色素P450亚酶CYP2B2(PROD)活性荧光定量检测试剂盒20次

RatFolicacid,FAELISAKit大鼠叶酸(FA)ELISA试剂盒规格：96T/48T

技术外包服务:

★B淋巴细胞诱导成熟蛋白1抗体说明书 分子生物学：质粒抽提、PCR、Q-PCR、RT-PCR、分子生物学：基因合成、引物合成、基因测序、载体构建等

★蛋白工程：原核、哺乳动物蛋白表达系统等

★病毒包装：腺病毒、慢病毒等

★抗体工程：磁珠分选、病理染色、WB、ELISA、IP、IF、IHC、FACS、Confocal等等

★细胞工程：细胞表型分析(凋亡、增殖、周期、迁移、侵袭、修复、克隆形成)、细胞培养、细胞膜制备、稳定细胞株构建、细胞RNAi技术等等。