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★蛋白酪氨酸磷酸酶H1抗体规格 分子生物学：质粒抽提、PCR、Q-PCR、RT-PCR、分子生物学：基因合成、引物合成、基因测序、载体构建等

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实验流程：

蛋白酪氨酸磷酸酶H1抗体规格 英文名称  Anti-PTPH1/PTPN3

中文名称  蛋白酪氨酸磷酸酶H1抗体规格 

别    名 cytoskeletal-associated protein tyrosine phosphatase; protein tyrosine phosphatase H1; protein tyrosine phosphatase non-receptor type 3; Protein-tyrosine phosphatase H1; PTN3_HUMAN; PTP H1; PTP-H1; PTPH1; PTPN3; Tyrosine-protein phosphatase non-receptor type 3.

产品属性：

浓    度  1mg/1ml

规 格  0.2ml/200μg

抗体来源  Rabbit

克隆类型   polyclonal

交叉反应   Human, Mouse, Rat, Dog, Cow, Horse, Sheep

产品类型   一抗  

研究领域     细胞生物 免疫学 信号转导 激酶和磷酸酶 细胞骨架

蛋白分子量  predicted molecular weight: 104kDa 

性    状   Lyophilized or Liquid

免 疫 原  KLH conjugated synthetic peptide derived from human PTPH1/PTPN3

亚    型  IgG

纯化方法   affinity purified by Protein A

储 存 液   Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4

蛋白酪氨酸磷酸酶H1抗体规格 产品应用   WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:50-200

（石蜡切片需做抗原修复） 

 not yet tested in other applications.

 optimal dilutions/concentrations should be determined by the end user.  

保存条件  Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. 

Important Note  This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. 

产品介绍 The phosphorylation of proteins at tyrosine residues has long been recognized as an important regulatory component of signal transduction. This is a reversible process, involving both enzymes that phosphorylate proteins on tyrosine residues as well as a rapidly expanding family of protein tyrosine phosphatases. These latter enzymes bear little resemblance to either the protein serine and protein threonine phosphatases or to the acid and alkaline phosphatases. In most tissues, the major PTPase is a vanadate- and molybdate-sensitive protein. PTP-H1 shares homology with the cytoskeletal-associated proteins band 4.1, ezrin, and talin and has been shown to contain a PDZ and band 4.1 domain. These domains are responsible for targeting proteins to the cytoskeleton-membrane interface, as well as mediating protein-protein interactions, recognizing C-terminal valine residues and binding to other PDZ domains. Overexpression of PTP-H1 may reverse transformation induced by oncogenic protein-tyrosine kinases, such as the members of the src family.

Function : May act at junctions between the membrane and the cytoskeleton. Possesses tyrosine phosphatase activity.

Subcellular Location : Cell membrane. Cytoplasm. cytoskeleton.

Similarity : Belongs to the protein-tyrosine phosphatase family. Non-receptor class subfamily.

Contains 1 PDZ (DHR) domain.

Contains 1 tyrosine-protein phosphatase domain.

Database links : UniProtKB/Swiss-Prot: P26045.2

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蛋白酪氨酸磷酸酶H1抗体规格 全：公司提供上万种产品，涵盖了生物试剂，elisa试剂盒，标准品，培养基，原装耗材，抗体、培养基、ATCC细胞等，基本上各种科研所需产品在我司都能找到。

新：产品更新速度较快，基本上每周都有新产品出现。

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