技术外包服务:

★胞粘蛋白结合调节蛋白抗体费用 分子生物学：质粒抽提、PCR、Q-PCR、RT-PCR、分子生物学：基因合成、引物合成、基因测序、载体构建等

★蛋白工程：原核、哺乳动物蛋白表达系统等

★病毒包装：腺病毒、慢病毒等

★抗体工程：磁珠分选、病理染色、WB、ELISA、IP、IF、IHC、FACS、Confocal等等

★细胞工程：细胞表型分析(凋亡、增殖、周期、迁移、侵袭、修复、克隆形成)、细胞培养、细胞膜制备、稳定细胞株构建、细胞RNAi技术等等。

实验流程：

胞粘蛋白结合调节蛋白抗体费用 英文名称  Anti-PSCDBP/CYTIP

中文名称  胞粘蛋白结合调节蛋白抗体费用 

别    名 B31; CASP; Cbp HE; CYBR; CYTHIP; Cytip; CYTIP_HUMAN; Cytohesin binder and regulator; Cytohesin-associated scaffolding protein; Cytohesin-binding protein HE; Cytohesin-interacting protein; HE antibody Pleckstrin Homology Sec7 and Coiled-Coil Domains Binding Protein; Pleckstrin homology Sec7 and coiled-coil domains-binding protein.

产品属性：

浓    度  1mg/1ml

规 格  0.2ml/200μg

抗体来源  Rabbit

克隆类型   polyclonal

交叉反应   Human, Mouse, Rat, Dog, Cow, Horse, Rabbit

产品类型   一抗  

研究领域    神经生物学 信号转导 转录调节因子 细胞粘附分子 表观遗传学

蛋白分子量  predicted molecular weight: 40kDa 

性    状   Lyophilized or Liquid

免 疫 原  KLH conjugated synthetic peptide derived from human PSCDBP/CYTIP

亚    型  IgG

纯化方法   affinity purified by Protein A

储 存 液   Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4

胞粘蛋白结合调节蛋白抗体费用 产品应用   WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500

（石蜡切片需做抗原修复） 

 not yet tested in other applications.

 optimal dilutions/concentrations should be determined by the end user.  

保存条件  Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. 

Important Note  This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. 

产品介绍 CYTIP is a cytoplasmic protein that is involved in lymphocytic cell adhesion. Expressed primarily in hematopoetic cells, CYTIP regulates the activity of cytohesin-1 (an integrin-activating protein involved in cell adhesion) by mediating its recruitment to the leukocyte membrane. Through its ability to bind cytohesin-1, CYTIP is able to sequester it to the cytoplasm, thereby preventing cytohesin-1 translocation to lymphocytes and interrupting the flow of information in the cell adhesion pathway. CYTIP can be recruited from the cytoplasm to the membrane by leukocyte integrins which interact with CYTIP through its PDZ domain. After membrane translocation, CYTIP can be re-located to the cytoplasm via exposure to a phorbol ester. Additionally, CYTIP associates with SNX27 (sorting nexin 27) and helps to coordinate trafficking and signaling complexes. Up-regulation of CYTIP is observed in maturing dendritic cells, suggesting a possible role in developmentally-controlled cell adhesion.

Function : By its binding to cytohesin-1 (CYTH1), it modifies activation of ARFs by CYTH1 and its precise function may be to sequester CYTH1 in the cytoplasm.

Subunit : Interacts with CYTH1 and SNX27.

Subcellular Location : Cytoplasm. Early endosome. Recruited from the cytosol to endosomes by SNX27.

Similarity : Contains 1 PDZ (DHR) domain.

Database links : UniProtKB/Swiss-Prot: O60759.2

全、新、优、品、好四大特点：

胞粘蛋白结合调节蛋白抗体费用 全：公司提供上万种产品，涵盖了生物试剂，elisa试剂盒，标准品，培养基，原装耗材，抗体、培养基、ATCC细胞等，基本上各种科研所需产品在我司都能找到。

新：产品更新速度较快，基本上每周都有新产品出现。

优：产品质量好，投诉比较少。

好：我公司具有优质的技术团队，产品一旦售出，实验过程中遇到困难可提供在线技术咨询。使您使用产品时没有任何的后顾之忧。

正在热销的相关产品：

CINC(human) 中性粒细胞趋化因子(人)Multi-class antibodies规格： 48T

Anti-CK18 细胞角蛋白18抗体Multi-class antibodies规格： 0.1ml

Rhesus antibody Rh NSP5 核结构蛋白5抗体 规格 0.2ml

Protein Marker 预染宽范围蛋白质分子量标准(19-117KD)/6条带 50次

RNF16 英文名称： 环指蛋白16抗体 0.2ml

C4orf51 英文名称： 4号染色体开放阅读框51抗体 0.2ml

Anti-CK18 细胞角蛋白18抗体Multi-class antibodies规格： 0.1ml

MDC/CCL22 ELISA Kit 大鼠巨噬细胞来源的趋化因子Multi-class antibodies规格： 48T

Anti-CEA/Gold 胶体金标记癌胚抗原抗体IgGMulti-class antibodies规格： 0.2ml

Rhesus antibody Rh FbxL12 FBXL12蛋白抗体 规格 0.2ml

VEGF-B(Human Vascular Endothelial cell Growth Factor B) ELISA KIT 人内皮细胞生长因子B 96T

phospho-MAP4K1(Ser171) 英文名称： 磷酸化造血祖细胞激酶抗体 0.1ml

ACPT 英文名称： 酸性磷酸酶抗体 0.2ml

Anti-CEA/Gold 胶体金标记癌胚抗原抗体IgGMulti-class antibodies规格： 0.2ml

Anti-IL-12R Beta2/FITC 荧光素标记白细胞介素-12受体β2抗体IgGMulti-class antibodies规格： 0.2ml

Anti-Phospho-PTEN (Ser380/Thr382/Thr383)/FITC 荧光素标记磷酸化抑制基因PTEN抗体IgGMulti-class antibodies规格： 0.2ml

Rhesus antibody Rh APLP1 淀粉样蛋白β前体样蛋白1抗体 规格 0.2ml

Rabbit Anti-rat IgM/Alexa Fluor 647 Alexa Fluor 647标记的兔抗大鼠IgM 0.1ml

GGCT 英文名称： γ-谷酰基环转移酶抗体 0.2ml

Rhesus antibody Rh Rabbit Anti-human sIgA/Cy5.5 Cy5.5标记的兔抗人分泌型IgA 规格 0.1ml

Anti-Phospho-PTEN (Ser380/Thr382/Thr383)/FITC 荧光素标记磷酸化抑制基因PTEN抗体IgGMulti-class antibodies规格： 0.2ml

大鼠巨噬细胞替代激活相关化学因子1(AmAC-1)ELISA试剂盒 ，英文名： AmAC-1 ELISA Kit

人碱性成纤维细胞生长因子4(bFGF-4)ELISA检测试剂盒Humanbasicfibroblastgrowthfactor4,bFGF-4ELISAKit 96T/48T

细小病毒(PPV)核酸检测试剂盒(PCR-荧光探针法) 48T

CLIAKitforNGF(MouseNervegrowthfactor)ELISAkit小鼠神经生长因子规格：48T/96T

体液D-葡萄糖激酶法定量检测试剂盒20次

ELISAKitTU3A人TU3A蛋白规格：48T/96T

大鼠白介素19(IL19)ELISA试剂盒 ，英文名： IL19 ELISA Kit

People with acridine orange (AO) ELISA Kit 人橙(AO)ELISA试剂盒

BovinesolubleClusterofdiffereiation86,sCD86ELISAKit 牛可溶性白细胞分化抗原86(B7-2/sCD86)ELISA试剂盒 96T/48T 进口分装

CLIAKitforCK(HumanCreatineKinase)ELISAKit人肌酸激酶规格：48T/96T

细胞脂质过氧化物亚油酸(linoleicacid)细胞流式分析试剂盒10次

RatBonemorphogeneticproteieceptor1A,BMPR-1AELISAKit大鼠骨成型蛋白受体1A(BMPR-1A)ELISA试剂盒规格：96T/48T

胞粘蛋白结合调节蛋白抗体费用 大鼠补体因子D(adipsin)(CFD)ELISA试剂盒 ，英文名： CFD ELISA Kit

Mouse substance P receptor (SP-R) ELISA Kit 小鼠P物质受体(SP-R)ELISA试剂盒

ELISA 小鼠D-二聚体(mouse D-Dimer) 48T/96T 进口分装

CLIAKitforLAT(MouseLinkerforactivationofTcell)ELISAKit小鼠T细胞活化连接蛋白规格：48T/96T

通用型VZV(VARICELLAZOSTER)病毒定性检测试剂盒20次

ELISAKitSCT鲑鱼降钙素规格：48T/96T