全、新、优、品、好四大特点：

原钙粘附蛋白8抗体品牌 全：公司提供上万种产品，涵盖了生物试剂，elisa试剂盒，标准品，培养基，原装耗材，抗体、培养基、ATCC细胞等，基本上各种科研所需产品在我司都能找到。

新：产品更新速度较快，基本上每周都有新产品出现。

优：产品质量好，投诉比较少。

好：我公司具有优质的技术团队，产品一旦售出，实验过程中遇到困难可提供在线技术咨询。使您使用产品时没有任何的后顾之忧。

原钙粘附蛋白8抗体品牌 英文名称  Anti-PCDH8

中文名称  原钙粘附蛋白8抗体品牌 

别    名 Arcadlin; PAPC; PCDH 8; Protocadherin 8; Protocadherin8; PCDH8_HUMAN.

产品属性：

浓    度  1mg/1ml

规 格  0.2ml/200μg

抗体来源  Rabbit

克隆类型   polyclonal

交叉反应   Human, Mouse, Rat, Pig, Cow, Rabbit, Goose, Sheep, Chimpanzee

产品类型   一抗  

研究领域    神经生物学 信号转导 细胞粘附分子 细胞骨架 细胞外基质 细胞膜蛋白

蛋白分子量  predicted molecular weight: 110kDa 

性    状   Lyophilized or Liquid

免 疫 原  KLH conjugated synthetic peptide derived from human PCDH8

亚    型  IgG

纯化方法   affinity purified by Protein A

储 存 液   Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4

原钙粘附蛋白8抗体品牌 产品应用   WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500

（石蜡切片需做抗原修复） 

 not yet tested in other applications.

 optimal dilutions/concentrations should be determined by the end user.  

保存条件  Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. 

Important Note  This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. 

产品介绍 Protocadherins are a large family of cadherin-like cell adhesion proteins that are involved in the establishment and maintenance of neuronal connections in the brain. There are three protocadherin gene clusters, designated alpha, beta and gamma, all of which contain multiple tandemly arranged genes. PCDH8 (protocadherin-8), also known as Arcadlin or PAPC, is a 1,070 amino acid single-pass type I membrane protein that contains six cadherin domains and belongs to the protocadherin family. Localized to the cell membrane and expressed specifically in fetal and adult brain, PCDH8 is thought to play a role in cell adhesion events in the central nervous system (CNS). PCDH8 is inactivated or silenced in breast cancer, suggesting a possible role in tumor suppression. Two isoforms of PCDH8 that differ in their cytoplasmic tails are expressed due to alternative splicing events.

Function : PCDH8 (Protocadherin 8) belongs to the protocadherin gene family, a subfamily of the cadherin superfamily. It is thought to function in cell-adhesion in a calcium-dependent manner. It is predominantly expressed in brain, localizing to synaptic junctions.

Subunit : The N-terminal extracellular domain forms homophilic interactions; these interactions activate p38 MAPK via TAOK2 and trigger endocytosis (By similarity). Interacts with CDH2; this interaction may lead to CDH2 cointernalization (By similarity). Interacts with CDH11 (By similarity). Interacts with TAOK2 (By similarity).

Subcellular Location : Cell Membrane. Single-pass type I membrane protein.

Database links : UniProtKB/Swiss-Prot: O95206.2

实验流程：

正在热销的相关产品：

MCV(Human anti-mutated citrullinated vimentin antibody) ELISA Kit 人型瓜氨酸波形蛋白抗体Multi-class antibodies规格： 48T

Anti-phospho-IKK alpha (Ser176 + Ser180) 磷酸化KB抑制蛋白激酶α抗体Multi-class antibodies规格： 0.1ml

Rhesus antibody Rh MAGEA5 相关抗原5抗体 规格 0.2ml

Lp-PL-A2(Human lipoprotein-associated phospholipase A2) ELISA Kit 人脂蛋脂酶A2 96T

RNF185 英文名称： 环指蛋白185抗体 0.2ml

CYP3A4 英文名称： 细胞色素P450 3A4抗体 0.1ml

Anti-phospho-IKK alpha (Ser176 + Ser180) 磷酸化KB抑制蛋白激酶α抗体Multi-class antibodies规格： 0.1ml

IFI16/p16(Mouse interferon-inducible protein 16) ELISA Kit 小鼠γ干扰素诱导蛋白16/p16Multi-class antibodies规格： 48T

Anti-Cdkn1c/p57/Kip2 /FITC 荧光素标记周期蛋白依赖激酶抑制因子1C抗体IgGMulti-class antibodies规格： 0.2ml

Rhesus antibody Rh Donkey Anti-Goat IgG/PE-Cy3 PE-Cy3标记的驴抗羊IgG 规格 0.1ml

LH Poultry ELISA Kit LH 禽类酶联免疫ELISA试剂盒 96T

LIM protein 英文名称： 相关蛋白抗体 0.1ml

phospho-Amyloid Precursor Protein (Thr668) 英文名称： 磷酸化APP淀粉样肽前体蛋白抗体 0.1ml

Anti-Cdkn1c/p57/Kip2 /FITC 荧光素标记周期蛋白依赖激酶抑制因子1C抗体IgGMulti-class antibodies规格： 0.2ml

Anti-OLFM1/FITC 荧光素标记兔抗人、大、小鼠、马、鸡嗅球蛋白1抗体IgGMulti-class antibodies规格： 0.2ml

Anti-PALB2/FITC 荧光素标记癌易感基因相关蛋白2IgGMulti-class antibodies规格： 0.2ml

Rhesus antibody Rh BCL2L15 BCL2样15促凋亡蛋白抗体 规格 0.2ml

FUCA1/Alpha L fucosidase I peptide α-L岩藻糖苷酶抗原 0.5mg

GFP 英文名称： 绿色荧光蛋白抗体 0.1ml

Rhesus antibody Rh RABGAP1 Rab蛋白GTP酶激活蛋白1抗体 规格 0.2ml

Anti-PALB2/FITC 荧光素标记癌易感基因相关蛋白2IgGMulti-class antibodies规格： 0.2ml

大鼠精胺脲水解酶(AGMAT)ELISA试剂盒 ，英文名： AGMAT ELISA Kit

人纤连蛋白(FN)ELISA检测试剂盒HumanFibronectin,FNELISAKit 96T/48T

伪毒(PRV)核酸检测试剂盒 48T

CLIAKitforNGF-Beta(HumanNervegrowthfactor-Beta)ELISAkit人的神经生长因子-β规格：48T/96T

体液EBV(EPSTEIN-BARR)病毒定量PCR扩增检测试剂盒20次

ELISAKitTIEG1人TGF-β诱导早期基因1规格：48T/96T

大鼠白介素17(IL-17)ELISA 试剂盒 96T/48T 试剂盒 组装/原装

人流行性脑脊髓膜炎抗体(IgM)免疫试剂盒 Human epidemic cerebrospinal meningitis aibody IgM ELISA Kit

PlaVitaminD,VDELISAKit植物维生素D(VD)ELISA试剂盒规格：96T/48T

石蜡切片组织RHO蛋白表达NBT显色光学显微镜检测试剂盒10/20次

HumaeceptorⅢfoheFcregionofimmunoglobulinG,FcγRⅢELISA试剂盒人免疫球蛋白GFc段受体Ⅲ(FcγRⅢ/CD16)ELISA试剂盒规格：96T/48T

Humanypsinogen-2,y-ⅡELISAKit人胰蛋白酶原Ⅱ(y-Ⅱ)ELISA试剂盒规格：96T/48T

原钙粘附蛋白8抗体品牌 大鼠补体蛋白3(C3)ELISA试剂盒 ，英文名： C3 ELISA Kit

Mouse alpha 1 microglobulin (alpha 1-MG) ELISA Kit 小鼠α1微球蛋白(α1-MG)ELISA试剂盒

ELISA 小鼠噬酸性粒细胞趋化因子(mouse Eotaxin) 48T/96T 进口分装

CLIAKitforKLR(Humankillercelllectin-likereceptor)ELISAKit人杀伤细胞凝集素样受体规格：48T/96T

通用型半胱氨酸(cysteine)含量高效液相色谱法定量检测试剂盒20次

ELISAKitTPA大鼠组织多肽抗原规格：48T/96T

技术外包服务:

★原钙粘附蛋白8抗体品牌 分子生物学：质粒抽提、PCR、Q-PCR、RT-PCR、分子生物学：基因合成、引物合成、基因测序、载体构建等

★蛋白工程：原核、哺乳动物蛋白表达系统等

★病毒包装：腺病毒、慢病毒等

★抗体工程：磁珠分选、病理染色、WB、ELISA、IP、IF、IHC、FACS、Confocal等等

★细胞工程：细胞表型分析(凋亡、增殖、周期、迁移、侵袭、修复、克隆形成)、细胞培养、细胞膜制备、稳定细胞株构建、细胞RNAi技术等等。