突触富含脯氨酸膜蛋白7抗体品牌 英文名称  Anti-PRR7

中文名称  突触富含脯氨酸膜蛋白7抗体品牌 

别    名 Proline rich protein 7; Proline-rich protein 7; Prr7; PRR7_HUMAN; Synaptic proline rich membrane protein; Synaptic proline-rich membrane protein; transmembrane adaptor protein 3; TRAP3.

产品属性：

浓    度  1mg/1ml

规 格  0.2ml/200μg

抗体来源  Rabbit

克隆类型   polyclonal

交叉反应   Human, Mouse, Rat, Dog, Cow, Sheep

产品类型   一抗  

研究领域    神经生物学 信号转导 通道蛋白 细胞膜受体

蛋白分子量  predicted molecular weight: 31kDa 

性    状   Lyophilized or Liquid

免 疫 原  KLH conjugated synthetic peptide derived from human PRR7

亚    型  IgG

纯化方法   affinity purified by Protein A

储 存 液   Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4

突触富含脯氨酸膜蛋白7抗体品牌 产品应用   WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 Flow-Cyt=1:100-500 ICC=1:100-500 IF=1:100-500

（石蜡切片需做抗原修复） 

 not yet tested in other applications.

 optimal dilutions/concentrations should be determined by the end user.  

保存条件  Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. 

Important Note  This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. 

产品介绍 PRR7 (proline rich 7), also known as Synaptic proline-rich membrane protein, is a 269 amino acid protein expressed in postsynaptic density (PSD) of the forebrain, especially in hippocampus. The proline rich sequence for which the protein is named is characteristic of a region that is involved in protein-protein interactions, acting as a ligand for SH3, WW and EVH1 domains. As a single-pass type III membrane protein, evidence shows that PRR7 forms a postsynaptic membrane complex with PSD-95 and NMDAz1, suggesting its possible function in the modulation of neural activities. The expression pattern in brain also suggests that PRR7 is essential for synaptic formation or maturation, specifically in the cerebrum. Two isoforms of PRR7 exist as a result of an alternative splicing event.

Subcellular Location : Membrane. Cell junction > synapse > postsynaptic cell membrane. Enriched in post-synaptic plasma membrane and postsynaptic densities (PSD). Accumulates in spines along with synapse maturation and colocalizes with DLG4 in a punctate pattern.

Database links : UniProtKB/Swiss-Prot: Q8TB68.1

实验流程：

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