全、新、优、品、好四大特点：

调亡诱导因子6相互作用蛋白/多巴胺受体相互作用蛋白4抗体费用 全：公司提供上万种产品，涵盖了生物试剂，elisa试剂盒，标准品，培养基，原装耗材，抗体、培养基、ATCC细胞等，基本上各种科研所需产品在我司都能找到。

新：产品更新速度较快，基本上每周都有新产品出现。

优：产品质量好，投诉比较少。

好：我公司具有优质的技术团队，产品一旦售出，实验过程中遇到困难可提供在线技术咨询。使您使用产品时没有任何的后顾之忧。

调亡诱导因子6相互作用蛋白/多巴胺受体相互作用蛋白4抗体费用 英文名称  Anti-PDC6I/Alix

中文名称  调亡诱导因子6相互作用蛋白/多巴胺受体相互作用蛋白4抗体费用 

别    名 AIP1; ALG 2 interacting protein 1; ALG-2-interacting protein 1; ALG2 interacting protein X; Alix; Apoptosis linked gene 2 interacting protein X; Dopamine receptor interacting protein 4; DRIP4; HP95; KIAA1375; MGC17003; PDC6I_HUMAN; PDCD6 interacting protein; PDCD6-interacting protein; PDCD6IP; Programmed cell death 6 interacting protein; Programmed cell death 6-interacting protein.

产品属性：

浓    度  1mg/1ml

规 格  0.2ml/200μg

抗体来源  Rabbit

克隆类型   polyclonal

交叉反应   Human, Mouse, Rat

产品类型   一抗  

研究领域    细胞生物 信号转导 细胞凋亡 转录调节因子

蛋白分子量  predicted molecular weight: 95 kDa 

性    状   Lyophilized or Liquid

免 疫 原  KLH conjugated synthetic peptide derived from human PDC6I(607-641aa)

亚    型  IgG

纯化方法   affinity purified by Protein A

储 存 液   Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4

调亡诱导因子6相互作用蛋白/多巴胺受体相互作用蛋白4抗体费用 产品应用   WB=1:100-500 ELISA=1:500-1000 IP=1:20-100 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500

（石蜡切片需做抗原修复） 

 not yet tested in other applications.

 optimal dilutions/concentrations should be determined by the end user.  

保存条件  Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. 

Important Note  This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. 

产品介绍 Class E VPS protein involved in concentration and sorting of cargo proteins of the multivesicular body (MVB) for incorporation into intralumenal vesicles (ILVs) that are generated by invagination and scission from the limiting membrane of the endosome. Binds to the phospholipid lysobisphosphatidic acid (LBPA) which is abundant in MVBs internal membranes. The MVB pathway appears to require the sequential function of ESCRT-O, -I,-II and -III complexes. The ESCRT machinery also functions in topologically equivalent membrane fission events, such as the terminal stages of cytokinesis and enveloped virus budding (HIV-1 and other lentiviruses). Appears to be an adapter for a subset of ESCRT-III proteins, such as CHMP4, to function at distinct membranes. Required for completion of cytokinesis. Involved in HIV-1 virus budding. Can replace TSG101 it its role of supporting HIV-1 release; this function implies the interaction with CHMP4B. May play a role in the regulation of both apoptosis and cell proliferation.

Function : Class E VPS protein involved in concentration and sorting of cargo proteins of the multivesicular body (MVB) for incorporation into intralumenal vesicles (ILVs) that are generated by invagination and scission from the limiting membrane of the endosome. Binds to the phospholipid lysobisphosphatidic acid (LBPA) which is abundant in MVBs internal membranes. The MVB pathway appears to require the sequential function of ESCRT-O, -I,-II and -III complexes. The ESCRT machinery also functions in topologically equivalent membrane fission events, such as the terminal stages of cytokinesis and enveloped virus budding (HIV-1 and other lentiviruses). Appears to be an adapter for a subset of ESCRT-III proteins, such as CHMP4, to function at distinct membranes. Required for completion of cytokinesis. Involved in HIV-1 virus budding. Can replace TSG101 it its role of supporting HIV-1 release; this function implies the interaction with CHMP4B. May play a role in the regulation of both apoptosis and cell proliferation.

Subunit : Interacts with SH3KBP1. Interacts with PDCD6 and TSG101 in a calcium-dependent manner. Interacts with and SGSM3. Self-associates. Interacts with CHMP4A; the interaction is direct. Interacts with CHMP4B; the interaction is direct. Interacts with CHMP4C; the interaction is direct. Interacts with HIV-1 p6. Interacts with EIAV p9; the interaction has been shown in vitro. Interacts with CEP55; the interaction is direct; CEP55 binds PDCD6IP in a 2:1 stoechiometry. May interact with PDGFRB. Interacts with SH3GL1 and SH3GL2. Interacts with murine leukemia virus Gag polyprotein (via LYPX(n)L motif). Interacts with murine leukemia virus Gag polyprotein (via LYPX(n)L motif).

Subcellular Location : Cytoplasm, cytosol. Melanosome. Cytoplasm, cytoskeleton, centrosome. Note=Identified by mass spectrometry in melanosome fractions from stage I to stage IV. Colocalized with CEP55 in the midbody during cytokinesis. Colocalized with CEP55 at centrosomes of non-dividing cells.

Similarity : Contains 1 BRO1 domain.

实验流程：

正在热销的相关产品：

Anti-Phospho-PLC gamma 2 (Tyr1217) /FITC 荧光素标记磷酸化磷酯酶Cγ2抗体IgGMulti-class antibodies规格： 0.2ml

Anti-p-NFATc2/FITC 荧光素标记磷酸化NFATc2抗体IgGMulti-class antibodies规格： 0.2ml

Rhesus antibody Rh C10orf62 10号染色体开放阅读框62抗体 规格 0.2ml

NOS-2 (iNOS) Nitric Oxide Synthase,Inducible 合成酶-2(抗原) 0.5mg

HOXD8 英文名称： 同源盒转录因子8抗体 0.1ml

Rhesus antibody Rh RNF15 环指蛋白15抗体 规格 0.2ml

Anti-p-NFATc2/FITC 荧光素标记磷酸化NFATc2抗体IgGMulti-class antibodies规格： 0.2ml

DPD ELISA Kit 大鼠脱氧吡啶酚/脱氧吡啶啉Multi-class antibodies规格： 48T

Anti-Phospho-YAP1 (Tyr357) 磷酸化原癌基因Yes相关蛋白1抗体Multi-class antibodies规格： 0.1ml

Rhesus antibody Rh G protein beta 4/GNB4 G蛋白β4抗体/鸟嘌呤核苷酸结合蛋白β亚基4 规格 0.2ml

M-CSF(Mouse Macrophage Colony-Stimulating Factor) ELISA Kit 小鼠巨噬细胞集落刺激因子 96T

NAB2 英文名称： EGR1结合蛋白2抗体 0.1ml

ARFBP1 英文名称： ADP核糖基化因子结合蛋白抗体 0.2ml

Anti-Phospho-YAP1 (Tyr357) 磷酸化原癌基因Yes相关蛋白1抗体Multi-class antibodies规格： 0.1ml

EPI(Human Epinephrine/Adrenaline) ELISA Kit 人Multi-class antibodies规格： 48T

Anti-LHRH/GNRH 黄体激素释放激素类似物抗体Multi-class antibodies规格： 0.1ml

Rhesus antibody Rh KLK3/Prostate Specific Antigen 激肽释放酶3/舒素3抗体 规格 0.2ml

MN(Human metanephrine) ELISA Kit 人变 96T

Phospho-PPIG (Ser376) 英文名称： 磷酸化亲环蛋白(亲环素)PPIG抗体 0.2ml

CD161c 英文名称： CD161c抗体 0.2ml

Anti-LHRH/GNRH 黄体激素释放激素类似物抗体Multi-class antibodies规格： 0.1ml

CL-0407NCTC 1469(小鼠正常肝细胞)5×106cells/瓶×2

SELE Others Cynomolgus 食蟹猴 E-Selectin / CD62e / SELE 人细胞裂解液 (阳性对照)

人脑微内皮细胞RNAHBMEC miRNA5 μg

MCF-7/ADR细胞，人癌细胞(耐阿霉素) 早代小鼠胚胎成纤维细胞,MEF细胞 AGS人胃腺癌细胞

MKN45(人细胞) 5×106cells/瓶×2

HUVEC single donor Pellet 人脐内皮细胞团块 > 1 mio.cells 球状少突细胞培养基OsM

CL-0406NCI-H838(人非小细胞细胞)5×106cells/瓶×2

ANGPTL1 Others Canine 狗 ANGPTL1 / Angiopoietin-like 1 人细胞裂解液 (阳性对照)

人星形胶质细胞RNAHA miRNA5 μg

家兔皮肤细胞;DR-S1 神经母细胞瘤细胞，SH-SY5Y细胞 U14细胞，小鼠子细胞

人类成纤维细胞系;CNLMG-B5538SKIN

HA Others H1N1 甲型 H1N1 (A/Solomon Islands/3/2006) 血凝素HA1 (Hemagglutinin) 人细胞裂解液 (阳性对照)

调亡诱导因子6相互作用蛋白/多巴胺受体相互作用蛋白4抗体费用 CL Others Human 人 CL-1 / CL / Chymoypsin-like protease 人细胞裂解液 (阳性对照)

人牙龈成纤维细胞HGF

盘羊皮肤细胞;ASHS3

PG细胞，人肺巨细胞癌 小鼠巨噬细胞,Ana-1细胞 CM-R119大鼠晶状体上皮细胞完全培养基100mL

RWPE1(人上皮细胞) 5×106cells/瓶×2

Gibco E071000 MesenPRO RS? Medium 含2%血清(New Zealand origin) 1 kit

技术外包服务:

★调亡诱导因子6相互作用蛋白/多巴胺受体相互作用蛋白4抗体费用 分子生物学：质粒抽提、PCR、Q-PCR、RT-PCR、分子生物学：基因合成、引物合成、基因测序、载体构建等

★蛋白工程：原核、哺乳动物蛋白表达系统等

★病毒包装：腺病毒、慢病毒等

★抗体工程：磁珠分选、病理染色、WB、ELISA、IP、IF、IHC、FACS、Confocal等等

★细胞工程：细胞表型分析(凋亡、增殖、周期、迁移、侵袭、修复、克隆形成)、细胞培养、细胞膜制备、稳定细胞株构建、细胞RNAi技术等等。