磷酸化突触后密度蛋白93抗体规格 英文名称  Anti-Phospho-PSD93 (Tyr340)

中文名称  磷酸化突触后密度蛋白93抗体规格 

别    名 Channel associated protein of synapse 110; Channel associated protein of synapses 110kD; Channel-associated protein of synapse-110; Chapsyn 110; Chapsyn-110; Chapsyn110; discs large homolog 2; Discs, large homolog 2 (Drosophila); Disks large homolog 2; DKFZp781D1854; DKFZp781E0954; Dlg 2; dlg2; DLG2_HUMAN; Dlgh 2; Dlgh2; FLJ37266; Gm1197; MGC131811; Postsynaptic density protein PSD 93; Postsynaptic density protein PSD-93; Postsynaptic density protein PSD93; PSD 93; PSD93.

产品属性：

浓    度  1mg/1ml

规 格  0.1ml/100μg

抗体来源  Rabbit

克隆类型   polyclonal

交叉反应   Human, Mouse, Rat, Chicken, Dog, Horse

产品类型   一抗 磷酸化抗体  

研究领域    细胞生物 免疫学 神经生物学

蛋白分子量  predicted molecular weight: 98kDa 

性    状   Lyophilized or Liquid

免 疫 原  KLH conjugated synthesised phosphopeptide derived from human PSD93 around the phosphorylation site of Tyr340

亚    型  IgG

纯化方法   affinity purified by Protein A

储 存 液   0.01M PBS, pH 7.4 with 10 mg/ml BSA and 0.1% Sodium azide

磷酸化突触后密度蛋白93抗体规格 产品应用   WB=1:100-500 ELISA=1:500-1000 IP=1:20-100 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500

（石蜡切片需做抗原修复） 

 not yet tested in other applications.

 optimal dilutions/concentrations should be determined by the end user.  

保存条件  Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. 

Important Note  This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. 

产品介绍 PSD 93 is believed to participate in the clustering of certain proteins, including N-methyl-D-aspartate (NMDA) receptors and shaker-type potassium channels at the synaptic membrane. There are two principal modes of interaction between PSD 93 and other proteins. NMDA receptors and shaker-type potassium channels both share C-terminal sequence homology consisting of a threonine/serine-X-valine-COOH (T/SXV) motif. Other neuronal proteins that share this motif (beta 1 adrenergic receptor, some serotonin receptors, some sodium channel subunits, and additional potassium channel subunits) may interact with PSD 93 by binding to its PDZ domains. Neuronal nitric oxide synthase (nNOS), which lacks the T/SXV motif but which has its own PDZ domain, has been shown to associate with PSD 93 in vitro through a pseudo-homotypic PDZ-PDZ interaction.

Function : Required for perception of chronic pain through NMDA receptor signaling. Regulates surface expression of NMDA receptors in dorsal horn neurons of the spinal cord. Interacts with the cytoplasmic tail of NMDA receptor subunits as well as inward rectifying potassium channels. Involved in regulation of synaptic stability at cholinergic synapses. Part of the postsynaptic protein scaffold of excitatory synapses (By similarity).

Subunit : Interacts through its PDZ domains with NETO1. Interacts with NOS1/nNOS through second PDZ domain (By similarity). Interacts with KCNJ2/Kir2.1 (via C-terminus) through one of its PDZ domains. Interacts with FRMPD4 (via C-terminus). Interacts with LRFN1, LRFN2 and LRFN4. Interacts with FASLG.

Subcellular Location : Membrane; Lipid-anchor (By similarity). Cell junction, synapse, postsynaptic cell membrane, postsynaptic density (By similarity). Cell junction, synapse (By similarity). Note=Concentrated in soma and postsynaptic density of a subset of neurons (By similarity).

Similarity : Belongs to the MAGUK family.

Contains 1 guanylate kinase-like domain.

Contains 3 PDZ (DHR) domains.

Contains 1 SH3 domain.

Database links : UniProtKB/Swiss-Prot: Q15700.3

实验流程：

全、新、优、品、好四大特点：

磷酸化突触后密度蛋白93抗体规格 全：公司提供上万种产品，涵盖了生物试剂，elisa试剂盒，标准品，培养基，原装耗材，抗体、培养基、ATCC细胞等，基本上各种科研所需产品在我司都能找到。

新：产品更新速度较快，基本上每周都有新产品出现。

优：产品质量好，投诉比较少。

好：我公司具有优质的技术团队，产品一旦售出，实验过程中遇到困难可提供在线技术咨询。使您使用产品时没有任何的后顾之忧。

正在热销的相关产品：

Anti-BRCA1(mouse rat)/FITC 荧光素标记癌易感基因1抗体(小鼠 大鼠)IgGMulti-class antibodies规格： 0.2ml

Anti-GRO Beta/FITC 荧光素标记兔抗生长调节致癌基因β抗体IgGMulti-class antibodies规格： 0.2ml

Rhesus antibody Rh CIDE A DNA断裂因子相似蛋白A抗体 规格 0.2ml

C-jun/AP-1 (Oncoprotein C-jun：active protein 1) 原癌基因蛋白(活化蛋白1)(抗原) 0.5mg

IFI78 英文名称： 干扰素诱导蛋白P78抗体 0.2ml

Rhesus antibody Rh TNK1 非受体型酪氨酸蛋白激酶Tnk1抗体 规格 0.1ml

Anti-GRO Beta/FITC 荧光素标记兔抗生长调节致癌基因β抗体IgGMulti-class antibodies规格： 0.2ml

Human Triggering Receptor Expresses on Myeloid Cells-1,TREM-1 ELISA Kit 人髓系细胞触发受体-1Multi-class antibodies规格： 48T

Anti-Phospho-SATB1 (Ser47) 磷酸化核基质结合区结合蛋白1抗体Multi-class antibodies规格： 0.1ml

Rhesus antibody Rh Granzyme K 颗粒酶K抗体 规格 0.2ml

Human Pancreatic carcinoma markers-CA242 ELISA Kit 人*癌标志物CA242 96T

OIF 英文名称： 骨诱导因子抗体 0.2ml

BMP6 英文名称： 骨形态发生蛋白6抗体 0.1ml

Anti-Phospho-SATB1 (Ser47) 磷酸化核基质结合区结合蛋白1抗体Multi-class antibodies规格： 0.1ml

TPO-Ab ELISA Kit 大鼠抗甲状腺过氧化物酶抗体Multi-class antibodies规格： 48T

Anti-TEM 1/CD248 内涎蛋白/内皮唾液酸蛋白抗体Multi-class antibodies规格： 0.2ml

Rhesus antibody Rh Goat Anti-Bovine IgG/Cy7 Cy7标记的羊抗IgG 规格 0.1ml

AZT ELISA Kit 大鼠叠氮胸苷 96T

Phospho-NMDAR1 (Ser897) 英文名称： 磷酸化谷酸受体1抗体 0.1ml

BDKRB2 英文名称： 缓激肽B2受体抗体 0.2ml

Anti-TEM 1/CD248 内涎蛋白/内皮唾液酸蛋白抗体Multi-class antibodies规格： 0.2ml

CL-0096HCT 116(人细胞)5×106cells/瓶×2

SPG21 Others Human 人 SPG21 杆状病毒-昆虫细胞裂解液 (阳性对照)

人神经束膜细胞裂解物HPCL

TT细胞，人骨髓样细胞 人肾小球系膜细胞,HMC细胞 神经小胶质细胞Many types of cells包装：5 × 105次方(1ml)

兔肾细胞;RK13

SLIK1 Others Human 人 SLIK1 人细胞裂解液 (阳性对照)

CL-0095HCCC-9810(人肝内细胞)5×106cells/瓶×2

IgG4 Others Human 人 IgG4-Fc (108 Ser/Pro) 人细胞裂解液 (阳性对照)

小鼠肝星形细胞完全培养基 100mL

H322人非小细胞细胞 H322 cells in human non small cell lung cancer DMEM+10% FBS

OSM Protein Human 重组人 Oncostatin M / OSM 蛋白 (His 标签)

RWPE-2(人正常细胞) 5×106cells/瓶×2 CHRF(人巨核细胞)

磷酸化突触后密度蛋白93抗体规格 CD83 Others Cynomolgus 食蟹猴 CD83 人细胞裂解液 (阳性对照)

CL-0156MFC(小鼠细胞)5×106cells/瓶×2

人*细胞裂解物HHL

UACC812细胞，人导管瘤细胞 鼠腹水瘤,EAC-E2G8细胞 脑动脉平滑肌细胞Many types of cells包装：5 × 105次方(1ml)

BEL-7405(人细胞) 5×106cells/瓶×2

HPASMC Pellet 人肺动脉平滑肌细胞团块 > 1 mio.cells 人*细胞裂解物HHL

技术外包服务:

★磷酸化突触后密度蛋白93抗体规格 分子生物学：质粒抽提、PCR、Q-PCR、RT-PCR、分子生物学：基因合成、引物合成、基因测序、载体构建等

★蛋白工程：原核、哺乳动物蛋白表达系统等

★病毒包装：腺病毒、慢病毒等

★抗体工程：磁珠分选、病理染色、WB、ELISA、IP、IF、IHC、FACS、Confocal等等

★细胞工程：细胞表型分析(凋亡、增殖、周期、迁移、侵袭、修复、克隆形成)、细胞培养、细胞膜制备、稳定细胞株构建、细胞RNAi技术等等。