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| 产地 | 进口、国产 |
| 品牌 | 上海莼试 |
| 保存条件 | Store at -20 °C |
| 货号 | CS10715 |
| 应用范围 | WB=1:100-500 ELISA=1:500-1000 IP=1:20-100 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500 |
| CAS编号 | |
| 抗体名 | Anti-Phospho-PSD95 (Tyr236/Tyr240) |
| 克隆性 | |
| 靶点 | 详见说明书 |
| 适应物种 | 详见说明书 |
| 形态 | 详见说明书 |
| 宿主 | 详见说明书 |
| 亚型 | IgG |
| 标识物 | 详见说明书 |
| 浓度 | 1mg/1ml% |
| 免疫原 | KLH conjugated Synthesised phosphopeptide derived from human PSD95 around the phosphorylation site of Tyr236/Tyr240 |
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磷酸化突触后密度蛋白95抗体品牌 英文名称 Anti-Phospho-PSD95 (Tyr236/Tyr240)
中文名称 磷酸化突触后密度蛋白95抗体品牌
别 名 Discs large homolog 4; DLG 4; DLG4; Human post-synaptic density protein 95 ; Postsynaptic density protein 95; PSD 95; PSD-95; SAP 90; SAP90; Synapse associated protein 90.
产品属性:
浓 度 1mg/1ml
规 格 0.1ml/100μg
抗体来源 Rabbit
克隆类型 polyclonal
交叉反应 Human, Mouse, Rat, Dog, Pig, Cow, Rabbit
产品类型 一抗 磷酸化抗体
研究领域 免疫学 神经生物学
蛋白分子量 predicted molecular weight: 80kDa
性 状 Lyophilized or Liquid
免 疫 原 KLH conjugated Synthesised phosphopeptide derived from human PSD95 around the phosphorylation site of Tyr236/Tyr240
亚 型 IgG
纯化方法 affinity purified by Protein A
储 存 液 0.01M PBS, pH 7.4 with 10 mg/ml BSA and 0.1% Sodium azide
磷酸化突触后密度蛋白95抗体品牌 产品应用 WB=1:100-500 ELISA=1:500-1000 IP=1:20-100 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500
(石蜡切片需做抗原修复)
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
保存条件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
Important Note This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
产品介绍 postsynaptic density protein 95 is a molecular scaffolding protein that binds and clusters N-methyl-D-aspartate receptors at neuronal synapses; may be involved in guanine nucleotide-mediated signal transduction pathway. This gene encodes a member of the membrane-associated guanylate kinase (MAGUK) family. It heteromultimerizes with DLG2. With DLG2 it is recruited into the same NMDA receptor and potassium channel clusters. These two MAGUK proteins may interact at postsynaptic sites to form a multimeric scaffold for the clustering of receptors, ion channels, and associated signaling proteins.
Subcellular Location : Cell membrane; Peripheral membrane protein. Cell junction, synapse, postsynaptic cell membrane, postsynaptic density. Cell junction, synapse. Cell junction, synapse, synaptosome (By similarity).
Tissue Specificity : Brain.
Similarity : Belongs to the MAGUK family.
Contains 3 PDZ (DHR) domains.
Contains 1 SH3 domain.
该蛋白质PSD95能夠帮助建立神经突触的架构,并且促成突触其他部分的成熟,例如加強目标細胞上的glutamate受体的聚集、增加树突棘(dendritic spines)的数量和大小以及增加神神经传导物质glutamate (谷氨酸盐)释放的量。这种蛋白质与阿滋海默症有关。
实验流程:

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