中文名称  Rho GTP酶激活蛋白29抗体规格 

英文名称  Anti-Rho GTPase activating protein 29

别    名 ARHGAP 29; ARHGAP29; ARHGAP29 protein; MGC166097; PARG 1; PARG1; PTPL1 associated RhoGAP 1; PTPL1-associated RhoGAP protein 1; RHG29_HUMAN; Rho GTPase acti ating protein 29; Rho GTPase acti ating protein 29 isoform CRA_a; Rho GTPase acti ating protein 29 isoform CRA_b; Rho GTPase-acti ating protein 29; Rho-type GTPase-acti ating protein 29.

产品属性：

Rho GTP酶激活蛋白29抗体规格 浓    度  1mg/1ml

规 格  0.2ml/200μg

抗体来源  Rabbit

克隆类型   polyclonal

交叉反应   Human, Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit

产品类型   一抗  

研究领域     信号转导 G蛋白信号

蛋白分子量  predicted molecular weight: 142kDa 

性    状   Lyophilized or Liquid

免 疫 原  KLH conjugated synthetic peptide derived from human PARG1

亚    型  IgG

纯化方法   affinity purified by Protein A

储 存 液   0.01M PBS, pH 7.4 with 10 mg/ml BSA and 0.1% Sodium azide

Rho GTP酶激活蛋白29抗体规格 产品应用   WB=1:100-500 ELISA=1:500-1000 IP=1:20-100 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500

（石蜡切片需做抗原修复） 

 not yet tested in other applications.

 optimal dilutions/concentrations should be determined by the end user.  

保存条件  Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. 

Important Note  This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. 

产品介绍 Rho GTPase activating protein 29 is a GTPase activator for the Rho-type GTPases. It converts them to an inactive GDP-bound state. It has strong activity toward RHOA and weaker activity toward RAC1 and CDC42. It also may act as a specific effector of RAP2A to regulate Rho. There are two named isoforms produced by alternative splicing. Rho GTPase activating protein 29 is widely expressed; highly expressed in skeletal muscle and heart; expressed at intermediate level in placenta, liver and pancreas; weakly expressed in brain, lung and kidney.

Function : GTPase activator for the Rho-type GTPases by converting them to an inactive GDP-bound state. Has strong activity toward RHOA, and weaker activity toward RAC1 and CDC42. May act as a specific effector of RAP2A to regulate Rho. In concert with RASIP1, suppresses RhoA signaling and dampens ROCK and MYH9 activities in endothelial cells and plays an essential role in blood vessel tubulogenesis.

Subunit : Interacts with PTPN13/PTPL1. Interacts with RAP2A via its coiled coil domain. Interacts with RASIP1 (By similarity).

Tissue Specificity : Widely expressed. Highly expressed in skeletal muscle and heart. Expressed at intermediate level in placenta, liver and pancreas. Weakly expressed in brain, lung and kidney.

Similarity : Contains 1 phorbol-ester/DAG-type zinc finger.

Contains 1 Rho-GAP domain.

Database links : UniProtKB/Swiss-Prot: Q52LW3.2

实验流程：

全、新、优、品、好四大特点：

Rho GTP酶激活蛋白29抗体规格 全：公司提供上万种产品，涵盖了生物试剂，elisa试剂盒，标准品，培养基，原装耗材，抗体、培养基、ATCC细胞等，基本上各种科研所需产品在我司都能找到。

新：产品更新速度较快，基本上每周都有新产品出现。

优：产品质量好，投诉比较少。

好：我公司具有优质的技术团队，产品一旦售出，实验过程中遇到困难可提供在线技术咨询。使您使用产品时没有任何的后顾之忧。

技术外包服务:

★Rho GTP酶激活蛋白29抗体规格 分子生物学：质粒抽提、PCR、Q-PCR、RT-PCR、分子生物学：基因合成、引物合成、基因测序、载体构建等

★蛋白工程：原核、哺乳动物蛋白表达系统等

★病毒包装：腺病毒、慢病毒等

★抗体工程：磁珠分选、病理染色、WB、ELISA、IP、IF、IHC、FACS、Confocal等等

★细胞工程：细胞表型分析(凋亡、增殖、周期、迁移、侵袭、修复、克隆形成)、细胞培养、细胞膜制备、稳定细胞株构建、细胞RNAi技术等等。

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