技术外包服务:

★ATP调节钾离子通道ROM K抗体规格 分子生物学：质粒抽提、PCR、Q-PCR、RT-PCR、分子生物学：基因合成、引物合成、基因测序、载体构建等

★蛋白工程：原核、哺乳动物蛋白表达系统等

★病毒包装：腺病毒、慢病毒等

★抗体工程：磁珠分选、病理染色、WB、ELISA、IP、IF、IHC、FACS、Confocal等等

★细胞工程：细胞表型分析(凋亡、增殖、周期、迁移、侵袭、修复、克隆形成)、细胞培养、细胞膜制备、稳定细胞株构建、细胞RNAi技术等等。

实验流程：

ATP调节钾离子通道ROM K抗体规格 英文名称  Anti-ROM-K/KCNJ1

中文名称  ATP调节钾离子通道ROM K抗体规格 

别    名 ROM K; ROM-K; inwardly rectifying subfamily J member 1; ATP regulated potassium channel ROM K; ATP sensitive inward rectifier potassium channel 1; ATP-regulated potassium channel ROM-K; ATP-sensitive inward rectifier potassium channel 1; Inward rectifier K(+) channel Kir1.1; inwardly rectifying K+ channel; IRK1_HUMAN; KCNJ 1; KCNJ; Kcnj1; Kir 1.1; Kir1.1; Potassium channel; Potassium channel inwardly rectifying subfamily J member 1; potassium inwardly-rectifying channel J1; ROMK 1; ROMK 2; ROMK; ROMK1; ROMK2.

产品属性：

浓    度  1mg/1ml

规 格  0.2ml/200μg

抗体来源  Rabbit

克隆类型   polyclonal

交叉反应   Human, Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit

产品类型   一抗  

研究领域    细胞生物 信号转导 通道蛋白

蛋白分子量  predicted molecular weight: 45kDa 

性    状   Lyophilized or Liquid

免 疫 原  KLH conjugated synthetic peptide derived from human ROM-K/KCNJ1

亚    型  IgG

纯化方法   affinity purified by Protein A

储 存 液   Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4

ATP调节钾离子通道ROM K抗体规格 产品应用   WB=1:100-500 ELISA=1:500-1000 IP=1:20-100 IHC-P=1:100-500 IHC-F=1:100-500 IF=1:100-500

（石蜡切片需做抗原修复） 

 not yet tested in other applications.

 optimal dilutions/concentrations should be determined by the end user.  

保存条件  Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. 

Important Note  This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. 

产品介绍 Potassium channels are present in most mammalian cells, where they participate in a wide range of physiologic responses. The protein encoded by this gene is an integral membrane protein and inward-rectifier type potassium channel. It is activated by internal ATP and probably plays an important role in potassium homeostasis. The encoded protein has a greater tendency to allow potassium to flow into a cell rather than out of a cell. Mutations in this gene have been associated with antenatal Bartter syndrome, which is characterized by salt wasting, hypokalemic alkalosis, hypercalciuria, and low blood pressure. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008].

Function : In the kidney, probably plays a major role in potassium homeostasis. Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it. Their voltage dependence is regulated by the concentration of extracellular potassium; as external potassium is raised, the voltage range of the channel opening shifts to more positive voltages. The inward rectification is mainly due to the blockage of outward current by internal magnesium. This channel is activated by internal ATP and can be blocked by external barium.

Subunit : Interacts with SGK1 and SLC9A3R2/NHERF2.

Subcellular Location : Membrane; Multi-pass membrane protein.

Tissue Specificity : In the kidney and pancreatic islets. Lower levels in skeletal muscle, pancreas, spleen, brain, heart and liver.

Post-translational modifications : Phosphorylation at Ser-44 by SGK1 is necessary for its expression at the cell membrane.

DISEASE : Defects in KCNJ1 are the cause of Bartter syndrome type 2 (BS2) [MIM:241200]; also termed hyperprostanglandin E syndrome 2. BS refers to a group of autosomal recessive disorders characterized by impaired salt reabsorption in the thick ascending loop of Henle with pronounced salt wasting, hypokalemic metabolic alkalosis, and varying degrees of hypercalciuria. BS2 is a life-threatening condition beginning in utero, with marked fetal polyuria that leads to polyhydramnios and premature delivery. Another hallmark of BS2 is a marked hypercalciuria and, as a secondary consequence, the development of nephrocalcinosis and osteopenia.

Similarity : Belongs to the inward rectifier-type potassium channel (TC 1.A.2.1) family. KCNJ1 subfamily.

Database links : UniProtKB/Swiss-Prot: P48048.1

全、新、优、品、好四大特点：

ATP调节钾离子通道ROM K抗体规格 全：公司提供上万种产品，涵盖了生物试剂，elisa试剂盒，标准品，培养基，原装耗材，抗体、培养基、ATCC细胞等，基本上各种科研所需产品在我司都能找到。

新：产品更新速度较快，基本上每周都有新产品出现。

优：产品质量好，投诉比较少。

好：我公司具有优质的技术团队，产品一旦售出，实验过程中遇到困难可提供在线技术咨询。使您使用产品时没有任何的后顾之忧。

正在热销的相关产品：

Lep IgG(Human Leptospira IgG) ELISA Kit 人钩端螺旋体IgGMulti-class antibodies规格： 48T

Anti-KCNA7 电压阀门通道混合器相关亚家族成员7抗体Multi-class antibodies规格： 0.2ml

Rhesus antibody Rh Layilin 透明质酸受体抗体 规格 0.1ml

SS(Human Somatostatin) ELISA Kit 人生长抑素 96T

PSMD6 英文名称： 蛋白酶调解因子6抗体 0.2ml

CASKIN2 英文名称： 皮肤相互作用蛋白2抗体 0.1ml

Anti-KCNA7 电压阀门通道混合器相关亚家族成员7抗体Multi-class antibodies规格： 0.2ml

Anti-P-cadherin/FITC 荧光素标记P-钙粘附分子抗体IgGMulti-class antibodies规格： 0.2ml

Mouse Anti-goat IgG/FITC 荧光素标记小鼠抗羊IgGMulti-class antibodies规格： 0.3ml

防御素β2抗体 Anti-Defensin β2 0.1ml

Mouse Anti-human IgG/Bio 生物素标记的小鼠抗人IgG 0.1ml

FRS2 英文名称： 成纤维细胞生长因子受体底物2抗体 0.2ml

Rhesus antibody Rh phospho-TrkB (Tyr705) 磷酸化酪氨酸激酶B抗体 规格 0.1ml

Mouse Anti-goat IgG/FITC 荧光素标记小鼠抗羊IgGMulti-class antibodies规格： 0.3ml

PDGF-BB 大鼠血小板衍生生长因子-BBMulti-class antibodies规格： 48T

Anti-Phospho-EGFR(Tyr1045) 磷酸化表皮生长因子受体抗体Multi-class antibodies规格： 0.1ml

Rhesus antibody Rh MYOG/Myogenin 肌红蛋白抗体(肌细胞生成素) 规格 0.1ml

mIgA(Human membrane IgA) ELISA Kit 人表面膜免疫球蛋白A 96T

SP6 英文名称： 转录因子SP6抗体 0.1ml

Contactin 6 英文名称： 神经细胞NB3特定蛋白抗体 0.2ml

Anti-Phospho-EGFR(Tyr1045) 磷酸化表皮生长因子受体抗体Multi-class antibodies规格： 0.1ml

H2STestMediumAgar

FWA淡水鱼类琼脂培养基 250g 用于淡水鱼类肠道内细菌检测

李氏菌选择性培养基基础(MMA) Modified Mcbride Agar Base 250 用于单增李氏菌选择性分离(SN标准)

胰酪胨大豆肉汤250g/瓶用于金黄色葡萄球菌的增菌和MPN试验incubationmedia胰酪胨大豆肉汤250g/瓶用于金黄色葡萄球菌的增菌和MPN试验

即用型管装培养基

TrypticaseSoy-YeastExtractBroth

酪蛋白琼脂 Casein Agar 用于蜡样芽孢杆菌的酪蛋白分解试验

卵黄甘露醇高盐琼脂基础 Egg-Yolk Mannitol Salt Agar Base 250克 金黄色葡萄球菌的分离培养

2×YT培养基250g/瓶用于重组大肠杆菌菌株的培养incubationmedia2×YT培养基250g/瓶用于重组大肠杆菌菌株的培养

肠球菌、溶血性链球菌和粪链球菌检验培养基

ATP调节钾离子通道ROM K抗体规格 奈瑟氏菌属细菌生化鉴定盒  规格：  8种×10次/盒  用途：  用于奈瑟氏菌属细菌生化鉴定

霍乱弧菌生化鉴定盒  规格：  11种×10次  用途：  霍乱弧菌生化鉴定

弧菌科细菌生化鉴定盒（16种×5次）  规格：  16种×5次  用途：  弧菌的生化鉴定

麦氏比浊管  规格：  1套/盒  用途：