全、新、优、品、好四大特点：

RAS癌基因相关蛋白RAB17抗体品牌 全：公司提供上万种产品，涵盖了生物试剂，elisa试剂盒，标准品，培养基，原装耗材，抗体、培养基、ATCC细胞等，基本上各种科研所需产品在我司都能找到。

新：产品更新速度较快，基本上每周都有新产品出现。

优：产品质量好，投诉比较少。

好：我公司具有优质的技术团队，产品一旦售出，实验过程中遇到困难可提供在线技术咨询。使您使用产品时没有任何的后顾之忧。

RAS癌基因相关蛋白RAB17抗体品牌 英文名称  Anti-Rab17

中文名称  RAS癌基因相关蛋白RAB17抗体品牌 

别    名 Rab 17; Rab17; RAB17 member RAS oncogene family; RAB17_HUMAN; Ras related protein Rab 17; Ras related protein Rab17; Ras-related protein Rab-17; FLJ12538; OTTHUMP00000164417; OTTHUMP00000202805.

产品属性：

浓    度  1mg/1ml

规 格  0.2ml/200μg

抗体来源  Rabbit

克隆类型   polyclonal

交叉反应   Human, Mouse, Rat, Dog

产品类型   一抗  

研究领域     信号转导 G蛋白信号

蛋白分子量  predicted molecular weight: 23kDa 

性    状   Lyophilized or Liquid

免 疫 原  KLH conjugated synthetic peptide derived from human Rab17

亚    型  IgG

纯化方法   affinity purified by Protein A

储 存 液   Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4

RAS癌基因相关蛋白RAB17抗体品牌 产品应用   WB=1:100-500 ELISA=1:500-1000 IHC-P=1:100-500 IHC-F=1:100-500 ICC=1:100-500 IF=1:100-500

（石蜡切片需做抗原修复） 

 not yet tested in other applications.

 optimal dilutions/concentrations should be determined by the end user.  

保存条件  Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. 

Important Note  This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. 

产品介绍 Rab17 belongs to the Rab family of small Ras-like GTPases. It is specifically expressed in epithelial cells and is upregulated during cell polarization. Immunofluorescence staining studies indicate that Rab17 is associated with the perinuclear recycling endosome in nonpolarized epithelial cells and with the apical recycling endosome in polarized epithelial cells. The function of Rab17 remains unclear. Reports of Rab17 colocalization with internalized IgA in the apical endosome suggest that it may regulate receptor-mediated transcytosis. Rab17 has also been shown to regulate melanocytic filopodia formation and melanosome trafficking. siRNA knockdown of Rab17 in melanoma cells induces melanosome accumulation in the cell periphery.

Function : The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different set of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion. That Rab is involved in transcytosis, the directed movement of endocytosed material through the cell and its exocytosis from the plasma membrane at the opposite side. Mainly observed in epithelial cells, transcytosis mediates for instance, the transcellular transport of immunoglobulins from the basolateral surface to the apical surface. Most probably controls membrane trafficking through apical recycling endosomes in a post-endocytic step of transcytosis. Required for melanosome transport and release from melanocytes, it also regulates dendrite and dendritic spine development (By similarity). May also play a role in cell migration.

Subcellular Location : Recycling endosome membrane; Lipid-anchor; Cytoplasmic side (By similarity). Cell projection, dendrite (By similarity). Note=May also localize at the basolateral and apical plasma membrane. In neurons, localizes to the cell body and dendritic shaft and spine (By similarity).

Tissue Specificity : Expressed in melanocytes (at protein level).

Similarity : Belongs to the small GTPase superfamily. Rab family.

Database links : UniProtKB/Swiss-Prot: Q9H0T7.2

实验流程：

正在热销的相关产品：

GLUT3(Glucose transporter 3) 葡萄糖转运蛋白3抗原Multi-class antibodies规格： 0.5mg

L1CAM CD171 / N-CAML1 / L1CAM 鼠单抗 (PE) Human

Rhesus antibody Rh Phospho-Cyclin B1(Ser133) 磷酸化周期素B1抗体 规格 0.1ml

Western转膜液 1L 自产

Zic2 英文名称： 锌指蛋白Zic2抗体 0.2ml

DAZ1 英文名称： 缺失基因1抗体 0.2ml

L1CAM CD171 / N-CAML1 / L1CAM 鼠单抗 (PE) Human

Anti-TSHR(CT)/FITC 荧光素标记促甲状腺素受体抗体(C端)IgGMulti-class antibodies规格： 0.2ml

TmR2(GDNFR Beta;TRN-R;GFR-alpha-2;NTNR-2) 胶质细胞系源性神经营养因子(多肽)Multi-class antibodies规格： 0.5mg

卵黄蛋白原抗体 Anti-VTG 0.2ml

Phospho-MEK4 (Ser257) 英文名称： 磷酸化原活化蛋白激酶激酶4抗体 0.1ml

LPA3 英文名称： 溶血磷脂酸受体蛋白3抗体 0.2ml

Rhesus antibody Rh phospho-IKK beta(Tyr188) 磷酸化KB抑制蛋白激酶β抗体 规格 0.1ml

TmR2(GDNFR Beta;TRN-R;GFR-alpha-2;NTNR-2) 胶质细胞系源性神经营养因子(多肽)Multi-class antibodies规格： 0.5mg

ZNF423 英文名称： 锌指蛋白423抗体 0.2ml

phospho-DNA PKcs (Ser2056) 英文名称： 磷酸化DNA依赖性蛋白激酶抗体 0.1ml

抗激素/升压素抗体 Anti-ADH/AVP 0.1ml

Anti-CD93/C1qrp/FITC 荧光素标记CD93抗体IgGMulti-class antibodies规格： 0.2ml

Rhesus antibody Rh phospho-FANCD2(Ser222) 磷酸化FANCD2抗体 规格 0.1ml

Cripto-1(C-Terminus) 衍化生长因子抗原(表皮生长因子相关肽)C端Multi-class antibodies规格： 0.5mg

VEGFA Protein Mouse 重组小鼠 VEGFA / VEGF164 蛋白

IMR-32 人神经母细胞瘤细胞

IL12A & IL12B Others Mouse 小鼠 IL12A & IL12B Heterodimer 人细胞裂解液 (阳性对照)

CEM/C1人急性淋巴细胞细胞 CEM/C1 human acute lymphoblastic leukemia cells RPMI-1640(GIBCO)+10%FBS

绵羊肺细胞;OAR-L1

小鼠垂体细胞(MPC)(5×105) 5637, 人细胞 Human

CL-0362HS 683(人脑细胞)5×106cells/瓶×2

DPP7 Others Mouse 小鼠 DPP7 / DPPII / DPP2 人细胞裂解液 (阳性对照)

小鼠成纤维细胞完全培养基 100mL

BALB/3T3 clone A31小鼠胚胎成纤维细胞 BALB/3T3 clone A31 mouse embryo fibroblasts DMEM培养基+10%FBS

IL36A Protein Human 重组人 IL1F6 / IL36A 蛋白

NCI-H358(人非小细胞细胞) 5×106cells/瓶×2 SH-SY5Y(神经母细胞瘤细胞)

RAS癌基因相关蛋白RAB17抗体品牌 VEGFA Protein Mouse 重组小鼠 VEGFA / VEGF164 蛋白

IMR-32 人神经母细胞瘤细胞

IL12A & IL12B Others Mouse 小鼠 IL12A & IL12B Heterodimer 人细胞裂解液 (阳性对照)

CEM/C1人急性淋巴细胞细胞 CEM/C1 human acute lymphoblastic leukemia cells RPMI-1640(GIBCO)+10%FBS

绵羊肺细胞;OAR-L1

小鼠垂体细胞(MPC)(5×105) 5637, 人细胞 Human

技术外包服务:

★RAS癌基因相关蛋白RAB17抗体品牌 分子生物学：质粒抽提、PCR、Q-PCR、RT-PCR、分子生物学：基因合成、引物合成、基因测序、载体构建等

★蛋白工程：原核、哺乳动物蛋白表达系统等

★病毒包装：腺病毒、慢病毒等

★抗体工程：磁珠分选、病理染色、WB、ELISA、IP、IF、IHC、FACS、Confocal等等

★细胞工程：细胞表型分析(凋亡、增殖、周期、迁移、侵袭、修复、克隆形成)、细胞培养、细胞膜制备、稳定细胞株构建、细胞RNAi技术等等。